Abstract: The prevention and control of COVID-19 has brought about many changes in the process and measures of air passenger safety travel, and maintaining the social distance requirement seriously affects the efficiency of boarding passengers with fast and efficient targets. Based on cellular automaton boarding simulation model, boarding strategies such as random (RD), outside-in (OI), back-to-front (BF), reverse pyramid (RP) and half-block (HB) were chosen to re-evaluate passenger boarding efficiency under the COVID-19 prevention and control. The sensitivity analysis of relevant influencing factors was carried out, and the operable countermeasures and combination of countermeasures that could restore boarding efficiency were put forward. The research shows that keeping social distance will prolong boarding time by an average of 2.4 ~ 2.8 times, resulting in a decline in the boarding efficiency of 58.0% ~ 64.1% of passengers. The aisle distance is the main factor affecting the boarding efficiency. Taking the random (RD) strategy as an example, the boarding efficiency decreases by 17.2% for every 0.4 m spacing increase. Using OI boarding strategy, restricting passengers carry-on luggage and using double cabin doors and other boarding strategies can recover an average of 3.0%, 3.2% and 27.9% of the efficiency loss, and using the combination of countermeasures can recover 40.3% of the efficiency loss, which can effectively recover the reduced boarding efficiency under the guarantee of the safety of epidemic prevention and control.