Abstract: In this paper, the principles of structural reliability calculations and calibration of the highway bridge structure desigh standards in force against the method of design checking calculation point are introduced. We can determine the reliability index β of the variant structural components by this method, which is one of the second moment probabilistic engineering design algorithms. This probabilistic design method is closely related to optimization in design. Some examples are given to illustrate the proposed method. A PC-1500 main program of computation of reliability β have been provided in the appendix of the paper.